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Effects of Adding End-Range Isometric Holds to Isotonic Knee Extensor Training on Isokinetic Performance in Sedentary Adults

NCT07667543 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 43

Last updated 2026-06-30

No results posted yet for this study

Summary

The goal of this clinical trial is to learn if adding a short muscle hold (isometric contraction) to a standard leg-strengthening exercise improves knee muscle strength more than the standard exercise alone, in healthy adults who do not exercise regularly. The main question it aims to answer is:

Does adding a 5-second hold at the end of each leg-extension exercise lead to greater gains in front-thigh muscle (quadriceps) strength than leg-extension exercise alone?

Researchers will compare two exercise groups to see if the added muscle hold makes a difference:

Group 1 will do leg-extension exercises with a 5-second hold added at the end of each repetition.

Group 2 will do the same leg-extension exercises without the added hold.

Participants will:

Do leg-extension exercises 3 days a week for 8 weeks Have their thigh muscle strength tested before and after the program using a special exercise machine Have their thigh size measured before and after the program

Conditions

  • Quadriceps Muscle Strength
  • Isokinetic

Interventions

OTHER

Isotonic Exercise With Added Isometric Hold

Isotonic knee-extension exercise (2 sets of 10 repetitions at 60% of 1-repetition maximum) performed 3 days per week for 8 weeks, with weekly load progression (\~5%) and 60 seconds of rest between sets. Each repetition concluded with a 5-second isometric hold of the lifted weight at 0° knee extension.

OTHER

Isotonic Exercise Only

Isotonic knee-extension exercise (2 sets of 10 repetitions at 60% of 1-repetition maximum) performed 3 days per week for 8 weeks, with weekly load progression (\~5%) and 60 seconds of rest between sets, without an added isometric hold.

Sponsors & Collaborators

  • Yeditepe University

    lead OTHER

Principal Investigators

  • Feyza Şule Hantal, PhD · Yeditepe University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-12-12
Primary Completion
2015-05-26
Completion
2015-07-06

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07667543 on ClinicalTrials.gov