HFpEF Phenotyping With Echo, Clinical, and Biomarkers

NCT07642921 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 500

Last updated 2026-06-11

No results posted yet for this study

Summary

The EPIC-HFpEF registry is a nationwide Italian study that follows people with a specific type of heart failure called HFpEF. About 500 patients will be enrolled from several specialized hospitals and monitored for up to two years, without changing their usual treatment.

The goal is to better understand this complex condition by identifying different patient "types" based on clinical features, heart imaging, and blood markers. Researchers will also look at how these groups are treated in real life and how their disease progresses over time.

By doing this, the study aims to improve how doctors classify and manage HFpEF, moving toward more personalized and effective care for patients in the future.

Conditions

  • Heart Failure With Preserved Ejection Fraction (HFPEF)

Sponsors & Collaborators

  • Azienda Ospedaliera di Perugia

    collaborator OTHER
  • Ospedale Le Scotte

    collaborator OTHER
  • University of Foggia

    collaborator OTHER
  • University Of Perugia

    lead OTHER

Principal Investigators

  • Erberto Carluccio, MD · Cardiology and Cardiovascular Pathophysiology Unit, University of Perugia and Azienda Ospedaliera di Perugia, Italy

  • Alberto Palazzuoli, MD · Cardio Thoracic and Vascular Department, Cardiovascular Diseases Unit, Le Scotte Hospital, Siena, Italy

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-06-02
Primary Completion
2027-06-30
Completion
2029-07-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07642921 on ClinicalTrials.gov