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Future Innovations in Novel Detection of Heart Failure FIND-HF

NCT05756127 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 14000

Last updated 2025-03-30

No results posted yet for this study

Summary

Heart failure (HF) is increasingly common and associated with excess morbidity, mortality and healthcare costs. New medications are now available which can alter the disease trajectory and reduce clinical events. However, many cases of HF remain undetected until presentation with more advanced symptoms, often requiring hospitalisation. Earlier identification and treatment of HF could reduce downstream healthcare impact, but predicting HF incidence is challenging due to the complexity and varying course of HF. The investigators will use routinely collected hospital-linked primary care data and focus on the use of artificial intelligence methods to develop and validate a prediction model for incident HF. Using clinical factors readily accessible in primary care, the investigators will provide a method for the identification of individuals in the community who are at risk of HF, as well as when incident HF will occur in those at risk, thus accelerating research assessing technologies for the improvement of risk prediction, and the targeting of high-risk individuals for preventive measures and screening.

Conditions

Interventions

OTHER

Observational - no intervention given

Observational - no intervention given

Sponsors & Collaborators

  • Japan Foundation for Aging and Health

    collaborator OTHER

  • University of Leeds

    lead OTHER

Principal Investigators

  • Chris P Gale · University of Leeds

Eligibility

Min Age
16 Years
Max Age
120 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-04-01
Primary Completion
2025-12-31
Completion
2025-12-31

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05756127 on ClinicalTrials.gov