The Role of Epicardial Adiposity in Heart Failure With Preserved Ejection Fraction
NCT06768437 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 130
Last updated 2026-04-30
Summary
In this study the investigators are aiming to recruit 130 patients with heart failure with preserved ejection fraction who are obese and non-obese to undergo CT and MRI scans, as well as some other investigations including blood tests, to help investigate if having more fat around the heart leads to worse heart function in this condition. This may lead to the development of new treatments aimed at lowering fat levels around the heart and in the rest of the body, specifically to treat HFpEF.
Conditions
- Heart Failure With Preserved Ejection Fraction (HFPEF)
Sponsors & Collaborators
-
University of Leicester
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-02-12
- Primary Completion
- 2027-08-31
- Completion
- 2037-08-31
Countries
- United Kingdom
Study Locations
More Related Trials
-
Association Between Coronary and Peripheral Vascular Injury in Heart Failure Patients With Preserved Ejection Fraction.
NCT05884346 ·Status: UNKNOWN ·Phase: NA
-
Classification of Heart Failure With Preserved Ejection Fraction
NCT01030991 ·Status: COMPLETED
-
Characterization of Heart Failure With Preserved Ejection Fraction
NCT03197350 ·Status: RECRUITING ·Phase: NA
-
UK Heart Failure With Preserved Ejection Fraction
NCT05441839 ·Status: RECRUITING
-
Hospital Register of Decompensated Heart Failure With Preserved Ejection Fraction
NCT06114498 ·Status: ACTIVE_NOT_RECRUITING
-
Retrospective Observational Analysis of a Cohort With Heart Failure With Preserved Ejection Fraction
NCT04233086 ·Status: COMPLETED
-
Understanding and Treating Heart Failure With Preserved Ejection Fraction: Novel Mechanisms, Diagnostics and Potential Therapeutics
NCT02052804 ·Status: COMPLETED
-
Prediction of the Development of Heart Failure With Preserved Ejection Fraction
NCT04894968 ·Status: UNKNOWN
-
Value of Intense Phenotyping in Heart Failure With Preserved Ejection Fraction
NCT05479669 ·Status: RECRUITING
-
A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction
NCT05887271 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
Clinical Characteristics and Predictors of Adverse Outcomes in HFpEF
NCT06228807 ·Status: COMPLETED
-
Risk Factors In Heart Failure Patients With Preserved Ejection Fraction
NCT06487468 ·Status: COMPLETED
-
QUAD-HF - Prospective Registry of Patients With Incident Heart Failure and Left Ventricular Ejection Fraction <50%
NCT07174362 ·Status: RECRUITING
-
The Heart Failure With Preserved Ejection Fraction (HFpEF) Pathophysiology Study.
NCT03186833 ·Status: COMPLETED
-
Isometric Exercise Training in Participants With Heart Failure With Preserved Ejection Fraction
NCT05551663 ·Status: UNKNOWN ·Phase: NA
-
Cardiac Cachexia in Advanced Heart Failure
NCT06259045 ·Status: ACTIVE_NOT_RECRUITING
-
Incidence and Echocardiographic Predictors of HFpEF in High-Risk Population Afferent to Italian Echo-labs Network
NCT05753553 ·Status: UNKNOWN
-
Biomarkers in Patients With Suspected HFpEF
NCT06101693 ·Status: RECRUITING
-
Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction
NCT06517186 ·Status: RECRUITING
-
Weight Loss as Therapy for Heart Failure With Preserved Ejection Fraction
NCT02911337 ·Status: COMPLETED ·Phase: NA
-
Provocative Tests for HFpEF
NCT06309550 ·Status: RECRUITING
-
Optimising Management of Patients With Heart Failure With Preserved Ejection Fraction in Primary Care
NCT03617848 ·Status: COMPLETED
-
Feasibility Study of a New Peripheral Oedema Monitor for Heart Failure
NCT02993601 ·Status: COMPLETED
-
Bioimpedance in Overweight and Obese Patients With Acute Heart Failure
NCT05541068 ·Status: COMPLETED ·Phase: NA
-
PErirenal Adipose Tissue and RenaL Hemodynamics in Patients With Heart Failure With Preserved Ejection Fraction
NCT05219188 ·Status: UNKNOWN