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IL-34 Levels in Various Types of Periodontitis

NCT04223869 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2020-01-10

No results posted yet for this study

Summary

The objective of this study is to 1) identification of the impact of IL-34 on the pathogenesis of periodontal disease and determine whether any relationship among the existing levels of Gingival crevicular fluid (GCF) Interleukin 34( IL-34 )and GCF Receptor activator of nuclear factor -kB ligand (RANKL), osteoprotegerin (OPG) and RANKL/OPG ratio, as a mediator of bone resorption 2) analysis of the impact of non-surgical periodontal treatment on GCF IL-34 levels in patients with chronic periodontitis (CP) and aggressive periodontitis (AgP) and 3) to correlate between biochemical markers and clinical recordings

Conditions

  • Chronic Periodontitis
  • Aggressive Periodontitis

Interventions

OTHER

non-surgical periodontal treatment

scaling and root planing were performed

Sponsors & Collaborators

  • Bulent Ecevit University

    lead OTHER

Principal Investigators

  • Umut Ballı, PhD, DDS · Bülent Ecevit University Faculty of Dentistry

  • Figen Öngöz Dede, PhD, DDS · T.C. ORDU ÜNİVERSİTESİ

  • Şeyma Bozkurt Doğan, PhD, DDS · Ankara Yildirim Beyazıt University

  • Erdim Sertoğlu, PhD, DDS · Ankara Sağlık Bilimleri University

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-01-31
Primary Completion
2016-02-29
Completion
2017-05-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04223869 on ClinicalTrials.gov