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Systemic Sclerosis DIet for GastrointESTinal Symptoms

NCT07402226 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2026-03-24

No results posted yet for this study

Summary

This research will evaluate the effect of diets on bloating/distention, assess changes in abdominal pain, and overall gastrointestinal symptom burden in Systemic Sclerosis. The researchers will do this by comparing outcomes of people assigned to 3 different diets. Following the research specifics of the diets will be available upon contact with the details listed below.

Conditions

  • Systemic Sclerosis (SSc)

Interventions

BEHAVIORAL

Diet 1: Restriction of fermentable carbohydrates

6 weeks guided diet under the supervision of a dietician restricting fermentable carbohydrates known to trigger GI symptoms.

BEHAVIORAL

Diet 2: Elimination of foods harmful to gut barrier and microbiome

6 weeks guided diet under the supervision of a dietician eliminating of foods harmful to gut barrier and microbiome

BEHAVIORAL

Diet 3: Regular meal patterns, soluble fiber, and portion control

6 weeks guided diet under the supervision of a dietician emphasizing regular meal patterns, soluble fiber, and portion control.

Sponsors & Collaborators

Principal Investigators

  • Dinesh Khanna, MD, MSc · University of Michigan

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-03-16
Primary Completion
2027-04-30
Completion
2027-04-30

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07402226 on ClinicalTrials.gov