INVESTIGATION OF THE EFFECT OF DIFFERENT ACTIVATION TECHNIQUES ON TLR9, IL6, IL10, TNF-ALFA LEVELS IN HEALTHY AND TYPE 2 DIABETIC PATIENTS WITH APICAL PERIODONTITIS REQUIRING RETREATMENT
NCT07389772 · Status: ENROLLING_BY_INVITATION · Type: OBSERVATIONAL · Enrollment: 90
Last updated 2026-02-10
Summary
The subject of this thesis study is the effects of SWEEPS laser and ultrasonic activation methods on the immune response in the treatment of apical periodontitis in healthy individuals and patients with Type 2 diabetes requiring retreatment, based on a comparative investigation of Toll-like Receptor 9 (TLR-9), Interleukin-6 (IL-6) and Tumour Necrosis Factor alpha (TNF-α), and Interleukin-10 (IL-10) levels.
Conditions
Sponsors & Collaborators
-
bengisu yüksel
lead OTHER
Principal Investigators
-
dilek hancerliogulları, associate professor · Kırıkkale University
Eligibility
- Min Age
- 18 Years
- Max Age
- 50 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2026-01-28
- Primary Completion
- 2026-06-30
- Completion
- 2027-05-15
Countries
- Turkey (Türkiye)
Study Locations
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