Inflammatory Response and Gingival iNOS Levels in Diabetic vs. Non-Diabetic Periodontitis Patients
NCT06803836 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 118
Last updated 2025-02-04
Summary
This study investigates the relationship between Type 2 diabetes mellitus (T2DM), glycemic control, and periodontal disease. Researchers analyzed the levels of inducible nitric oxide synthase (iNOS) and proinflammatory cytokines, such as tumor necrosis factor-alpha (TNF-α), interleukin-1 beta (IL-1β), and interferon-gamma (IFN-γ), in 118 participants. The participants were categorized based on their periodontal and diabetes control status.
Conditions
- Periodontitis
- Type 2 Diabetes
- Glycemic Control
Sponsors & Collaborators
-
Ondokuz Mayıs University
lead OTHER
Principal Investigators
-
Sude YILDIRIM BOLAT, DDS · Ondokuz Mayıs University, Department of Periodontology
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2020-01-10
- Primary Completion
- 2022-01-10
- Completion
- 2022-03-10
Countries
- Turkey (Türkiye)
Study Locations
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