Electrophysiological Representations of Odor Identity Study 2

NCT07386236 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 28

Last updated 2026-02-04

No results posted yet for this study

Summary

To identify a neural representation of odor identity, it is necessary to dissociate molecular structure from perceptual identity/similarity.

Whether the olfactory system employs a coding scheme in which the similarity between neural features is systematically related to perceptual similarity is unknown. Experiments for this aim will acquire perceptual responses while manipulating perceptual similarity. In Experiment 1A, we will examine features of neural responses during natural behavior of freely naming odors. In Experiment 1B, we will manipulate perceptual similarity with odor metamers and collect perceptual and neural data on each trial. Preliminary data suggest that the earliest, high-frequency components of the piriform response can optimally decode perceptual identity.

Conditions

  • Odor Identity Ratings

Interventions

BEHAVIORAL

odor

present odor

Sponsors & Collaborators

Principal Investigators

  • christina zelano · Northwestern University

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
12 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-03-05
Primary Completion
2028-03-01
Completion
2028-10-01

Countries

  • United States

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07386236 on ClinicalTrials.gov