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The Role of 5-HT2A Receptor in the Perception of Self and Personal Meaning in Healthy Volunteers

NCT02451072 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 25

Last updated 2016-02-01

No results posted yet for this study

Summary

Aim of the present study is to investigate the neuronal correlates of self and of personal meaning as well as the role of the serotonin (5-HT) 2A receptor system in these processes using functional magnetic resonance imaging (fMRI) and psychometric and cognitive measures.

Conditions

  • Healthy

Interventions

DRUG

Placebo

Capsules containing mannitol looking identical to LSD per os

DRUG

LSD

100µg per os, single dose

DRUG

Ketanserin

40mg per os, single dose looking identical to LSD per os

Sponsors & Collaborators

  • Psychiatric University Hospital, Zurich

    lead OTHER

Principal Investigators

  • Franz X. Vollenweider, Prof. Dr. · Center for Psychiatric Research, Department of Psychiatry, Psychotherapy and Psychosomatic, Psychiatric Hospital, University of Zurich

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
SINGLE_GROUP

Eligibility

Min Age
20 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-03-31
Primary Completion
2016-01-31
Completion
2016-01-31

Countries

  • Switzerland

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02451072 on ClinicalTrials.gov