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Deep Breathing With and Without Pressure Support and PEEP for Preoxygenation in Obese Patients

NCT07380425 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 75

Last updated 2026-02-02

No results posted yet for this study

Summary

Obese patients are at increased risk of low oxygen levels during the induction of general anesthesia. Preoxygenation with a face mask before anesthesia is routinely used to increase oxygen reserves. This study compares three preoxygenation techniques: deep breathing alone, deep breathing with pressure-supported ventilation, and deep breathing with pressure-supported ventilation plus positive end-expiratory pressure (PEEP).

The main goal of the study is to determine how quickly each technique allows patients to reach an adequate level of oxygen in the lungs. In addition, the study evaluates whether these techniques cause gastric distension, which could increase the risk of regurgitation. Gastric ultrasound is used to assess stomach size before and after preoxygenation.

The results of this study will help identify the most effective and safest method of preoxygenation in obese patients undergoing elective surgery.

Conditions

Interventions

PROCEDURE

Deep Breathing Preoxygenation

Preoxygenation performed with deep breathing using a ventilator delivering 100% oxygen at a flow rate of 12 L/min.

PROCEDURE

Pressure Support Ventilation

Application of pressure support ventilation with a pressure support level of 12 cmH₂O during preoxygenation.

PROCEDURE

Positive End-Expiratory Pressure

Application of positive end-expiratory pressure at a level of 6 cmH₂O during preoxygenation.

Sponsors & Collaborators

  • Pamukkale University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-12-01
Primary Completion
2022-07-25
Completion
2022-07-25

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07380425 on ClinicalTrials.gov