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Ventilation Distribution After Bariatric Surgery

NCT03975348 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 15

Last updated 2020-07-30

No results posted yet for this study

Summary

Obese patients have an increased risk of developing post-operative respiratory complications due to their comorbidities. They have a restrictive ventilatory defect with reduction of lung volumes and expiratory flow limitation, higher airway resistance and collapsibility of the upper respiratory tract. These abnormalities are worsened by general anesthesia and opioid administration. It has been proved that oxygen therapy with HFNC (high flow nasal cannula) increases lung volumes through a continuous positive airway pressure (CPAP)-effect. This also improves gas exchange and decreases anatomical dead space. At the present time, CPAP represents the gold standard for the prevention of postoperative pulmonary complications. The purpose of this study is to evaluate lung ventilation, gas exchange and comfort with HFNC compared with CPAP during the post-operative period in patients who undergo laparoscopic bariatric surgery.

Conditions

  • Bariatric Surgery Candidate
  • Atelectasis, Postoperative Pulmonary

Interventions

DEVICE

High flow nasal cannula

High flow of warm and humidified oxygen/air mixture delivered through nasal cannula

DEVICE

Continuous positive airway pressure

Positive airway pressure applied through a sealed face mask

DEVICE

Facemask

Oxygen therapy through a conventional facemask

Sponsors & Collaborators

  • University of Trieste

    lead OTHER

Principal Investigators

  • Lucia Comuzzi · Azienda Sanitaria Universitaria Integrata di Trieste

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-04-15
Primary Completion
2019-09-30
Completion
2019-09-30

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03975348 on ClinicalTrials.gov