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Individualized vs Low PEEP in One Lung Ventilation

NCT03569774 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL

Last updated 2021-07-06

No results posted yet for this study

Summary

The aim of the prospective crossover study is to investigate the effect of individualized positive end-expiratory pressure (PEEP) on measures of tissue oxygenation, compared with low PEEP.

Conditions

  • One-Lung Ventilation
  • Obesity
  • Lung Diseases

Interventions

PROCEDURE

One-lung ventilation with individualized PEEP

During one-lung ventilation for lung resection surgery, PEEP will be applied. After a subject's individualized PEEP (PEEP that corresponds to maximum lung compliance) is determined, the subject will receive one-lung ventilation with individualized PEEP.

PROCEDURE

One-lung ventilation with low PEEP

Subjects will receive one-lung ventilation with low PEEP (5 cmH2O)

Sponsors & Collaborators

  • Dionne Peacher

    lead OTHER

Principal Investigators

  • Dionne Peacher, MD · University of Iowa

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-08-14
Primary Completion
2021-05-19
Completion
2021-05-19

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03569774 on ClinicalTrials.gov