MedTrace Logo

Optic Nerve Ultrasound for Assessing Cerebral Inflammation and Intracranial Hypertension in Cerebral Pathologies

NCT07332234 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2026-01-12

No results posted yet for this study

Summary

Timely detection of signs of raised intracranial pressure or persistent inflammation within the meninges can expedite therapeutic decisions improving the prognosis of patients with brain damage. Optic nerve ultrasonography provides a user-friendly, safe, low-cost, and non-invasive imaging method that can be easily deployed for ICU patient assessment. This study aims to evaluate the sensitivity and specificity of optic nerve ultrasound in estimating cerebral inflammation extension and cerebral edema in patients in the ICU. The working hypothesis is that optic nerve ultrasound is a useful tool in the rapid diagnosis of cerebral edema and the presence or persistence of cerebral inflammation, which can enable adapted and rapid therapeutic interventions.

Conditions

  • Meningitis
  • Meningitis/Encephalitis
  • Stroke
  • Ultrasound
  • Intracranial Hypertension
  • Cerebral Tumors

Interventions

DIAGNOSTIC_TEST

Optic Nerve Sheath Diameter

Ultrasonographic measurement of the optic nerve sheath diameter

Sponsors & Collaborators

  • Institutul Clinic Fundeni

    collaborator OTHER

  • Spitalul Clinic de Boli Infecțioase și tropicale "Dr. Victor Babeș"

    lead OTHER

Principal Investigators

  • Bogdan Pavel, MD, PhD, DESA · "Dr. Victor Babeș" Clinical Hospital for Infectious and Tropical Diseases

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-12-01
Primary Completion
2027-12-01
Completion
2027-12-01

Countries

  • Romania

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07332234 on ClinicalTrials.gov