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Giant Cell Arteritis: Improving Use of Ultrasound Evaluation

NCT02523625 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 250

Last updated 2015-08-14

No results posted yet for this study

Summary

Giant cell arteritis (GCA) is an inflammatory disease causing new, unaccustomed headache in the elderly and which can lead to blindness in 20-30% of untreated cases. The study group have previously shown that ultrasound is a viable non-invasive alternative to temporal artery biopsy in diagnosing GCA. However, there is significant variation in ultrasound assessment (measuring a dark "halo" around the abnormal blood vessels) between sonographers in different centres, requiring a labour intensive and time consuming training programme. The study group propose to standardise the training programme, and use ultrasound and clinical evaluation to define changes occurring over time and with treatment in patients with a diagnosis of GCA made based on ultrasound changes alone. The study group will explore the use of algorithms to automate or semi-automate image interpretation.

Conditions

  • Giant Cell Arteritis

Interventions

DEVICE

Ultrasound of temporal and axillary arteries

Each patient will have a clinical assessment and ultrasound examination of both temporal and axillary arteries

Sponsors & Collaborators

  • University of Lisbon

    collaborator OTHER

  • University of Oxford

    lead OTHER

Principal Investigators

  • Raashid A Luqmani, DM FRCP · University of Oxford

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-10-31
Primary Completion
2017-09-30
Completion
2018-06-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02523625 on ClinicalTrials.gov