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Developing and Validating Blood and Imaging BIOmarkers of AXonal Injury Following Traumatic Brain Injury

NCT03534154 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 313

Last updated 2022-03-31

No results posted yet for this study

Summary

Observational longitudinal study assessing outcomes following moderate-severe traumatic brain injury (TBI).

Conditions

Interventions

DIAGNOSTIC_TEST

MRI

Magnetic Resonance Imaging

DIAGNOSTIC_TEST

Blood Sampling

Sampling of serum

DIAGNOSTIC_TEST

Microdialysis

Monitoring of cerebral fluid protein levels

DIAGNOSTIC_TEST

Neuropsychological tests

Battery of tests to assess cognitive function, patient outcomes

DIAGNOSTIC_TEST

MRI (advanced)

Advanced MRI

Sponsors & Collaborators

  • Centre Hospitalier Universitaire Vaudois

    collaborator OTHER

  • University College, London

    collaborator OTHER

  • Istituto Di Ricerche Farmacologiche Mario Negri

    collaborator OTHER

  • Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

    collaborator OTHER

  • Imperial College London

    lead OTHER

Principal Investigators

  • David Sharp · Imperial College London

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-11-30
Primary Completion
2021-04-30
Completion
2021-12-30

Countries

  • Italy
  • Slovenia
  • Switzerland
  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03534154 on ClinicalTrials.gov