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Serum Chromium, Nickel, and Magnesium in Type 2 Diabetic Periodontitis

NCT07327086 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 74

Last updated 2026-01-08

No results posted yet for this study

Summary

Periodontitis is a chronic immunoinflammatory disease that has been increasingly associated with systemic conditions, particularly type 2 diabetes mellitus (T2DM). Trace elements such as chromium (Cr), magnesium (Mg), and nickel (Ni) play important roles in metabolic regulation, insulin signaling, inflammatory responses, and tissue integrity. Alterations in the serum levels of these elements have been reported in T2DM; however, their relationship with periodontal status remains poorly understood. This cross-sectional observational study aims to evaluate serum Cr, Mg, and Ni levels in individuals with T2DM and chronic periodontitis and to investigate their potential associations with periodontal clinical parameters.

Conditions

  • Type 2 Diabetes Mellitus (T2DM)
  • Periodontal Disease

Interventions

OTHER

No intervention (Observational study)

Participants were not assigned to any therapeutic or preventive intervention. The study involved periodontal examination and blood sample collection for serum trace element analysis only.

Sponsors & Collaborators

  • Kahramanmaras Sutcu Imam University

    lead OTHER

Principal Investigators

  • esra bozkurt · Kahramanmaras Sutcu Imam University

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-07-01
Primary Completion
2025-10-30
Completion
2025-10-30

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07327086 on ClinicalTrials.gov