Protease Regulation and Impact of Sodium as Mechanisms of Inflammation in IBD
NCT07169123 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 300
Last updated 2025-09-11
Summary
The study looks at how eating salt affects gut health in people with Crohn's disease. The aim of the study is to find out whether eating more salt increases the breakdown of proteins in the gut and if this makes inflammation and symptoms worse. By studying the link between salt, gut bacteria and inflammation, the study hopes to improve diet advice for people with Crohn's disease. This research may help find specific foods that affect the disease and lead to better, more personalized nutrition plans.
Conditions
- Crohns Disease
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
David Armstrong, MD · McMaster University
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-09-18
- Primary Completion
- 2029-09-01
- Completion
- 2029-09-01
Countries
- Canada
Study Locations
More Related Trials
-
The Impact of "Crohn's Disease-TReatment-with-EATing" Diet and Exclusive Enteral Nutrition on Healthy Gut Bacteria
NCT02426567 ·Status: COMPLETED ·Phase: NA
-
Impact of Diet and Lifestyle Modification on the Intestinal Barrier Integrity in Crohn's Disease
NCT06719778 ·Status: RECRUITING ·Phase: NA
-
Effect of the Consumption of a Probiotic Strain on the Prevention of Post-operative Recurrence in Crohn's Disease
NCT01698970 ·Status: COMPLETED ·Phase: NA
-
Study of Dietary Composition in Crohn's Disease
NCT04431700 ·Status: TERMINATED ·Phase: NA
-
Diet as Essential Therapy (DIET) for Inflammatory Bowel Disease
NCT03012542 ·Status: UNKNOWN ·Phase: NA
-
Can Intermittent Fasting Induce Weight Loss and Improve Gut Health as Compared to Standard Medical Care in Patients With Obesity/High BMI and Crohn's Disease.
NCT05230160 ·Status: UNKNOWN ·Phase: NA
-
Effect of SB CD on Chylomicron
NCT03496818 ·Status: COMPLETED
-
The Effect of Probiotics on Exacerbation of Inflammatory Bowel Disease Exacerbation (Crohn's Disease)
NCT01765998 ·Status: UNKNOWN ·Phase: PHASE4
-
The Effect of Exclusion Diet for Crohn's Disease Plus Enteral Nutrition on Children and Adolescents With Crohn's Disease
NCT06353633 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Predicting IBD Treatment Outcomes With Gut Microbiome Analysis
NCT06453720 ·Status: RECRUITING
-
A Crohn's Disease Diet to Reduce Symptoms of Crohn's Disease
NCT01897090 ·Status: WITHDRAWN ·Phase: NA
-
Immune Response Regulation and Nutritional Status of the Crohn's Disease Patients.
NCT01957423 ·Status: COMPLETED ·Phase: NA
-
Modeling Patient Response to a Therapeutic Diet in Crohn's Disease
NCT04596566 ·Status: UNKNOWN ·Phase: NA
-
Effect of Glutamine on Intestinal Permeability in Crohn's Disease
NCT00838149 ·Status: COMPLETED ·Phase: PHASE1
-
Proof of Concept Human Study: Dietary Intervention to Modify Intestinal Inflammation in IBD
NCT05867537 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Protein and Energy Metabolism in Pediatric Crohn's Disease
NCT00583232 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of a Comprehensive Nutrition Support Product on the Nutritional Status of Adults With Inflammatory Bowel Disease
NCT02801240 ·Status: COMPLETED ·Phase: NA
-
Whole-Food, Plant-Based Diet for Active Crohn's Disease
NCT04982666 ·Status: WITHDRAWN ·Phase: NA
-
Impact of Exclusive Enteral Nutrition Therapy on Sperm Quality of Patients With Crohn's Disease
NCT02233062 ·Status: COMPLETED ·Phase: NA
-
Tracking the Natural Course of Silent Small Bowel Narrowing in Adults With Crohn's Disease
NCT07167745 ·Status: COMPLETED
-
Exclusive Enteral Nutrition vs. Infliximab in Chinese CD Patients
NCT04530877 ·Status: WITHDRAWN ·Phase: PHASE4
-
Energy Expenditure in Patients With Crohn's Disease
NCT01622270 ·Status: UNKNOWN
-
Cranberry and Gut Health in Crohn's Disease
NCT07170462 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
The Effect of Diet on Microbial Profile and Disease Outcomes in Patients With Inflammatory Bowel Diseases
NCT02858557 ·Status: UNKNOWN ·Phase: NA
-
Crohn's Disease, Obesity and Disease Severity
NCT00488085 ·Status: UNKNOWN