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Crohn's Disease - Inflammation and Microbial Proteolytic Activity

NCT06503081 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2025-08-22

No results posted yet for this study

Summary

This study postulates that altered microbiota associated with areas of mucosal inflammation in CD, can be characterized by an increased proteolytic profile. This is clinically important as it may be possible to modulate the proteolytic activity of the CD-associated bacteria by using other bacteria that produce protease inhibitors, such as serpins.

Conditions

  • Crohn's Disease of Both Small and Large Intestine

Interventions

PROCEDURE

Colonoscopy

Colonoscopy with video recording and biopsy collection

Sponsors & Collaborators

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-12-01
Primary Completion
2025-02-20
Completion
2025-02-20

Countries

  • Canada

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06503081 on ClinicalTrials.gov