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Sarcopenia and Neuromuscular Block in Gastrointestinal Cancer Surgery

NCT07003061 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2026-04-30

No results posted yet for this study

Summary

This prospective observational study aims to evaluate the effects of sarcopenia on intraoperative neuromuscular block (NMB) in patients undergoing gastrointestinal cancer surgery. Adult patients scheduled for elective gastrointestinal cancer surgery will be grouped as sarcopenic or non-sarcopenic based on preoperative abdominal CT scans. Neuromuscular block parameters, including onset time, depth, duration, and recovery, will be objectively measured using TOF (Train-of-Four) monitoring. The study seeks to determine whether sarcopenia influences sensitivity to muscle relaxants and to contribute to individualized anesthesia management and patient safety.

Conditions

Interventions

PROCEDURE

Standard Anesthesia Management

All patients will receive standard anesthesia care as per institutional protocols. No experimental intervention will be applied.

Sponsors & Collaborators

  • Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

    lead OTHER

Principal Investigators

  • Mustafa Kemal SAHIN · Ankara Oncology Education and Research Hospital Clinic of Anesthesiology and Reanimation

  • Mensure KAYA · Ankara Oncology Education and Research Hospital Clinic of Anesthesiology and Reanimation

  • Belkis YILMAZ · Ankara Oncology Education and Research Hospital Clinic of Anesthesiology and Reanimation

  • Ahmet BAYRAK · Ankara Oncology Education and Research Hospital Clinic of Radiology

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-06-01
Primary Completion
2026-02-10
Completion
2026-04-01

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07003061 on ClinicalTrials.gov