Immunotherapy is increasingly used in earlier cancer stages before or after surgery across seven tumor areas. Research shows neoadjuvant and adjuvant immunotherapy can reduce recurrence risk and improve immune recognition of tumor cells. However, challenges remain including side effects, costs, and determining which patients benefit most from earlier treatment.
Colorectal cancer diagnoses in people under 50 now account for nearly half of all new cases, prompting specialized treatment programs that use precision medicine and liquid biopsy technology to customize care based on individual tumor genetics.
Pfizer reported positive Phase 3 trial results for BRAFTOVI combination therapy in metastatic colorectal cancer and received FDA Priority Review for HYMPAVZI expansion to hemophilia patients including children.
Immunotherapy is increasingly being used before and after surgery across seven cancer types, while the global immunotherapy drugs market experiences significant growth driven by advances in biotechnology and targeted therapies.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07590622 |
EAT-ING: Enhancing Anticancer Treatment Safety Via Immunomodulatory Nutritional Support in Advanced Gastrointestinal Cancers |
NOT_YET_RECRUITING | NA |
| NCT07575854 |
A Study of Selective Internal Radiation Therapy for the Management of Chemotherapy-induced Thrombocytopenia With Splenomegaly in Adult Subjects With Gastrointestinal Cancer |
NOT_YET_RECRUITING | NA |
| NCT07558447 |
Extracellular Vesicles and Chemotherapy-Induced Peripheral Neuropathy |
RECRUITING | NA |
| NCT07524114 |
Study of High-Precision Evaluation of Molecular ResiduaL Disease Through a PlatfOrm for Cancer TracKing and Interception (SHERLOCK) |
RECRUITING | |
| NCT07440290 |
DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers. |
NOT_YET_RECRUITING | PHASE2/PHASE3 |
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Food-related Quality of Life in Patients With Cancer |
NOT_YET_RECRUITING | |
| NCT07405307 |
Sarcopenia Risk Screening in Patients With Gastrointestinal Cancer Using SARC-F |
RECRUITING | |
| NCT07404527 |
Bioelectrical Impedance Analysis for Perioperative Fluid Evaluation in Colorectal Cancer Surgery |
RECRUITING | NA |
| NCT07329894 |
Safety, Tolerance and Preliminary Efficacy of XH001 Injection Combined With Neoantigen Vaccine-induced Tumor-specific T-cell Injection in Advanced Gastrointestinal Cancer |
RECRUITING | PHASE1 |
| NCT07263594 |
A Study of DB-1324 in Advanced/Metastatic Gastrointestinal Tumors |
RECRUITING | PHASE1/PHASE2 |
