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RAFT-TAVR PACE: LBBAP vs. RVP Post-TAVR in Patients Requiring PPI

NCT06857201 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL

Last updated 2026-04-21

No results posted yet for this study

Summary

The RAFT-TAVR PACE study is a clinical trial designed to compare two types of heart pacing methods in patients who develop conduction problems after undergoing a transcatheter aortic valve replacement (TAVR) procedure.

This study will evaluate whether Left Bundle Branch Area Pacing (LBBAP), a newer and more natural pacing method, is better than the traditional Right Ventricular Pacing (RVP) at improving heart function and patient outcomes.

The study aims to recruit 60 patients across six centers and will focus on the safety, feasibility, and success of LBBAP compared to RVP. Patients will be followed for one year to assess heart function, quality of life, and any complications related to the pacing method.

Conditions

  • High Degree Second Degree Atrioventricular Block
  • Complete Heart Block
  • Heart Failure
  • Transcatheter Aortic Valve Replacement (TAVR)
  • Conduction Disorder

Interventions

PROCEDURE

Left Bundle Branch Area Pacing

LBBAP is performed during permanent pacemaker implantation post-TAVR.

PROCEDURE

Right Ventricular Pacing

RVP is performed during permanent pacemaker implantation post-TAVR.

Sponsors & Collaborators

  • London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-04-16
Primary Completion
2026-04-16
Completion
2026-04-16

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06857201 on ClinicalTrials.gov