Reduction in Arrhythmia Burden With Left Atrial Posterior Wall Ablation for Persistent AF
NCT05195268 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL
Last updated 2022-09-29
Summary
RABLAP-AF will compare pulmonary vein isolation (PVI) in combination with posterior wall isolation (PWI) for patients with persistent atrial fibrillation (AF).
Conditions
Interventions
- PROCEDURE
-
Intracardiac Catheter Ablation
Both arms will receive intracardiac catheter ablation procedures as described.
Sponsors & Collaborators
-
Biosense Webster, Inc.
collaborator INDUSTRY -
Royal Brompton & Harefield NHS Foundation Trust
collaborator OTHER -
St George's University Hospitals NHS Foundation Trust
collaborator OTHER -
University Hospital Plymouth NHS Trust
collaborator OTHER -
South Tees Hospitals NHS Foundation Trust
collaborator OTHER -
Manchester University NHS Foundation Trust
collaborator OTHER_GOV -
Guy's and St Thomas' NHS Foundation Trust
collaborator OTHER -
Papworth Hospital NHS Foundation Trust
collaborator OTHER_GOV -
Portsmouth Hospitals NHS Trust
collaborator OTHER_GOV -
University Hospitals Dorset NHS Foundation Trust
collaborator OTHER_GOV -
University Hospital Birmingham NHS Foundation Trust
collaborator OTHER -
Onze Lieve Vrouw Hospital
collaborator OTHER -
AZ Sint-Jan AV
collaborator OTHER -
University of Liverpool
collaborator OTHER -
Liverpool Heart and Chest Hospital NHS Foundation Trust
lead OTHER
Principal Investigators
-
Dhiraj Gupta, MD · Liverpool Heart & Chest Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-07-01
- Primary Completion
- 2022-09-12
- Completion
- 2022-09-12
Countries
- United Kingdom
Study Locations
More Related Trials
-
Low Voltage-Directed Catheter Ablation for Atrial Fibrillation
NCT03355456 ·Status: RECRUITING ·Phase: NA
-
The Substrate and Intervention Mechanisms for Persistent Atrial Fibrillation Trial
NCT02918396 ·Status: TERMINATED ·Phase: NA
-
Randomized Trial of Segmental Versus Circumferential Antral Ablation in Paroxysmal Atrial Fibrillation
NCT01260220 ·Status: COMPLETED ·Phase: NA
-
Effect of Empirical Left Atrial Appendage Isolation on Long-term Procedure Outcome in Patients With Persistent or Long-standing Persistent Atrial Fibrillation Undergoing Catheter Ablation
NCT01362738 ·Status: COMPLETED ·Phase: PHASE3
-
Comparison of Two Pulmonary Vein Ablation Techniques for Persistent AF
NCT03295422 ·Status: UNKNOWN ·Phase: NA
-
Substrate Targeted Ablation Using the FlexAbility™ Ablation Catheter System for the Reduction of Ventricular Tachycardia
NCT02130765 ·Status: TERMINATED ·Phase: NA
-
Safety and Efficacy of Pulsed-field Ablation for Atrial Fibrillation in High Versus Low-volume Ablation Centers (SAFFICIENT)
NCT06488820 ·Status: TERMINATED
-
Left Atrial Ablation With Permanent Pacemaker or ImplanTable Loop Recorder Follow-UP
NCT01095770 ·Status: UNKNOWN ·Phase: NA
-
Non-invasive Characterization of the Mechanisms of Atrial Fibrillation Maintenance
NCT02497248 ·Status: COMPLETED
-
Ablation of the Pulmonary Veins for Paroxysmal Afib
NCT00744874 ·Status: COMPLETED ·Phase: PHASE4
-
Convergent Ablation Plus Left Atrial Appendage Isolation for the Treatment of Persistent Atrial Fibrillation
NCT06165510 ·Status: RECRUITING ·Phase: NA
-
Left Atrial Appendage Electrical Isolation and Occlusion to Treat Persistent Atrial Fibrillation: A Safety and Feasibility Study
NCT02028130 ·Status: UNKNOWN ·Phase: NA
-
Outcome of Atrial Fibrillation Ablation After Permanent Pulmonary Vein Antrum Isolation With or Without Proven Left Atrial Posterior Wall Isolation
NCT01660100 ·Status: COMPLETED ·Phase: NA
-
Comparison of Pulmonary Vein Ablation With or Without Left Atrial Posterior Wall Ablation for Persistent AF (PIVoTAL)
NCT03057548 ·Status: COMPLETED ·Phase: NA
-
The Low Voltage Guided Ablation Trial of Persistent Atrial Fibrillation
NCT02732626 ·Status: COMPLETED ·Phase: NA
-
PFA-based Bi-atrial Maze-like Catheter Ablation for PeAF
NCT06952023 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
FIRM Ablation Versus Pulmonary Vein Isolation for the Treatment of Paroxysmal Atrial Fibrillation (PAF)
NCT02703454 ·Status: TERMINATED ·Phase: NA
-
CardioFocus vs. Contact Force Guided Pulmonary Vein Isolation in Paroxysmal Atrial Fibrillation
NCT03056222 ·Status: COMPLETED ·Phase: NA
-
Evaluation of the Efficacy of Pulmonary Vein Isolation by Pulsed-field Ablation in Persistent Atrial Fibrillation: a Multicenter Study With Follow-up by Implantable Cardiac Monitor
NCT06985901 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Clinical Evaluation of Therapy™ Cool Flex Ablation Catheter for the Treatment of Paroxysmal Atrial Fibrillation
NCT01185613 ·Status: COMPLETED ·Phase: PHASE2
-
BaLloon-based PFA Ablation poST Approval Outcomes for PAF and PersAF
NCT07181590 ·Status: RECRUITING ·Phase: NA
-
Comparing Surgical Management Methods of Atrial Fibrillation
NCT07100483 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
The Effect of Pulse Field Ablation on Atrial Mechanics in Catheter Ablation of Paroxysmal Atrial Fibrillation
NCT06557876 ·Status: RECRUITING ·Phase: NA
-
Effect of Structural Remodeling on Scar Formation as Assessed by DE-MRI of the Left Atrium
NCT01187914 ·Status: COMPLETED
-
RAFT-TAVR PACE: LBBAP vs. RVP Post-TAVR in Patients Requiring PPI
NCT06857201 ·Status: WITHDRAWN ·Phase: NA