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Individualised Mapping in Persistent AF Ablation

NCT05065112 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 212

Last updated 2021-10-01

No results posted yet for this study

Summary

A clinical randomised trial to compare strategies for ablation in persistent and long-standing persistent atrial fibrillation comprising of two arms: pulmonary veins isolation (PVI) only and PVI + individualised mapping-guided ablation (Cartofinder, Biosense Webster Inc.)

Conditions

  • Persistent Atrial Fibrillation

Interventions

PROCEDURE

Pulmonary veins isolation + Cartofinder-guided ablation

The individualised mapping with Cartofinder intends to identify areas with the repetitive atrial activation patterns which are targeted with focal or linear ablation anchored on at least one end in an anatomical or electrical barrier.

PROCEDURE

Pulmonary veins isolation

Wide area circumferential pulmonary veins isolation

Sponsors & Collaborators

  • Royal Brompton & Harefield NHS Foundation Trust

    lead OTHER

Principal Investigators

  • Vias Markides, MD, FESC · Royal Brompton Hospital, London, UK

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-11-30
Primary Completion
2024-11-30
Completion
2025-05-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05065112 on ClinicalTrials.gov