Influence of Sarcopenia on the Course of the Diseases
NCT06829290 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2025-02-17
Summary
Frailty is a geriatric syndrome that primarily affects older patients, but also patients with severe illnesses. It is particularly common among oncology patients, but also among patients with gastrointestinal diseases such as liver cirrhosis or pancreatitis. Sarcopenia, a form of frailty, is defined as a loss of muscle quantity, quality and function. Currently, complex methods such as CT or bioimpedance measurement are available. However, simpler techniques such as ultrasound-based measurement could be alternatives, but still require further validation. In addition, serological muscle markers could support and simplify diagnostics.
The aim of this project is to be able to estimate the prognosis of patients at an early stage by measuring sarcopenia using ultrasound and biomarkers.
Conditions
- Liver Cirrhosis
- Cancer
- Cachexia
- Sarcopenia
- Mechanical Ventilation
Interventions
- DIAGNOSTIC_TEST
-
Ultrasound
Sonographisch measurement of muscles Blood muscle markers
Sponsors & Collaborators
-
Universitatsmedizin Mainz - 1. Medizinische Klinik
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-10-01
- Primary Completion
- 2026-10-01
- Completion
- 2028-10-01
Countries
- Germany
Study Locations
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