MedTrace Logo

Multicomponent Analysis of phYsical Frailty BiomarkErs: Focus on Mitochondrial Health - MAYBE

NCT05938205 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 111

Last updated 2023-07-10

No results posted yet for this study

Summary

The study will be conducted in a group of obese sarcopenic patients (Sarco-Ob) aged \> 60 years on moderately hypocaloric diet therapy aimed at comparing the effect of a strength exercise protocol, combined or not with dietary supplementation with amino acids, on physical performance, muscle strength, body composition, muscle oxidative metabolism, and biomarkers of sarcopenia. The supplementation study will be conducted in a double-blind manner.

Conditions

  • Sarcopenic Obesity
  • Frailty
  • Malnutrition; Protein

Interventions

DIETARY_SUPPLEMENT

AA-1

low dose aminoacids

DIETARY_SUPPLEMENT

AA-2

high dose aminoacids

BEHAVIORAL

Placebo

Nutritional Placebo

BEHAVIORAL

Exe-H

high intensity physical exercise

Sponsors & Collaborators

  • Università degli Studi di Brescia

    collaborator OTHER

  • Azienda Ospedaliera di Padova

    collaborator OTHER

  • University of Milan

    collaborator OTHER

  • Azienda Ospedaliera Universitaria Integrata Verona

    lead OTHER

Principal Investigators

  • Elena Zoico, PhD · Universita di Verona

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
60 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-03-01
Primary Completion
2022-07-06
Completion
2022-07-06

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05938205 on ClinicalTrials.gov