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Identifying Modifiable PAtient Centered Therapeutics (IMPACT) Frailty

NCT04717869 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 250

Last updated 2026-01-30

No results posted yet for this study

Summary

Frailty, the decline in physical and cognitive reserves leading to vulnerability to stressors is increasingly being recognized as a public health concern. Although multiple measures exist that can identify frail patients, very little is known about how or when to intervene. Sarcopenia, or the degree of muscle wasting, is closely correlated to frailty and patient outcomes. This is a prospective cohort study of critically ill patients to identify modifiable risk factors of sarcopenia, as potential targets to reduce frailty.

Conditions

Interventions

DIAGNOSTIC_TEST

Ultrasound

2D ultrasound image collection

DIAGNOSTIC_TEST

Biomarker Analysis

Inflammatory and nutritional biomarker analysis

OTHER

Frailty Index

A Frailty Index Questionnaire be completed by patients or their surrogates to determine the presence of frailty at ICU admission

Sponsors & Collaborators

Principal Investigators

  • Cecilia Canales, MD, MPH · UCLA Department of Anesthesiology and Perioperative Medicine

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-09-22
Primary Completion
2026-05-31
Completion
2026-07-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04717869 on ClinicalTrials.gov