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Inflammatory Stress and Periodontal Tissue Destruction

NCT06092853 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 80

Last updated 2023-10-23

No results posted yet for this study

Summary

Metabolic syndrome and periodontitis are diseases that lower the quality of life and their incidence rates are increasing. Since both of these diseases are associated with systemic inflammation and insulin resistance, they may be comorbid. The aim of this study was to evaluate the effect of interleukin-20 (IL-20) on periodontal destruction in individuals with metabolic syndrome while considering the relationship between metabolic syndrome and periodontitis.

This study included a total of 80 individuals who were systemically and periodontally healthy (CG, n=20), were systemically healthy and had periodontitis (PG, n=20), had metabolic syndrome and were periodontally healthy (MG, n=20), or had both metabolic syndrome and periodontitis (MPG, n=20). Gingival crevicular fluid (GCF) and serum samples were collected from all participants for biochemical analyses.

Conditions

Interventions

OTHER

Gingival crevicular fluid (GCF) and serum samples

Gingival crevicular fluid (GCF) and serum samples were collected from all participants for biochemical analyses

Sponsors & Collaborators

  • Recep Tayyip Erdogan University

    collaborator OTHER

  • Recep Tayyip Erdogan University Training and Research Hospital

    lead OTHER

Eligibility

Min Age
20 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-06-06
Primary Completion
2023-03-06
Completion
2023-06-06

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06092853 on ClinicalTrials.gov