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Investigation of the Etiology of Hypertension and Endothelial Damage in Patients With Cytochrome P450 Oxidoreductase Deficiency

NCT06756620 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 51

Last updated 2025-09-08

No results posted yet for this study

Summary

This study investigates the etiology of hypertension and endothelial damage in patients with Cytochrome P450 Oxidoreductase (POR) deficiency. The study involves comparing ambulatory blood pressure monitoring (ABPM), endothelial biomarkers (Prostaglandin E2, Thromboxane B2, and Nitric Oxide levels), and capillaroscopy findings between POR deficiency patients and healthy controls.

Conditions

  • Cytochrome P450 Oxidoreductase Deficiency
  • Hypertension
  • Endothelial Dysfunction
  • Congenital Adrenal Hyperplasia

Sponsors & Collaborators

  • The Scientific and Technological Research Council of Turkey

    collaborator OTHER

  • Istanbul University

    collaborator OTHER

  • Ozge Bayrak Demirel

    lead OTHER

Principal Investigators

  • Ozge Bayrak Demirel, MD · Istanbul University

Eligibility

Min Age
7 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-12-24
Primary Completion
2025-08-12
Completion
2025-08-12

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06756620 on ClinicalTrials.gov