Comparison of Efficacy of Betamethasone Gel With Lidocaine Gel in Prevention of Post Endotracheal Intubation Sore Throat.
NCT07256834 · Status: NOT_YET_RECRUITING · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2025-12-01
Summary
The goal of this clinical trial is to compare the incidence of postoperative sore throat in adult patients of either gender belonging to ASA I or II ,undergoing endotracheal intubation using betamethasone gel versus lidocaine gel. It aims to determine
1: Difference in efficacy of Betamethasone gel and lidocaine gel in prevention of post operative sore throat after endotracheal intubation.
Patients will be assessed for the presence of a sore throat at 6 hours and 24 hours postoperatively. The severity of the sore throat will be graded using the Post-Operative Sore Throat (POST) score.
Conditions
- Post Operative Sore Throat at 6hrs and 24hrs After Endotracheal Intubation
Interventions
- DRUG
-
Betamethasone dipropionate 0.05%
It is corticosteroid indicated for relief of inflammatory and pruritic manifestation
- DRUG
-
Lidocaine hydrochloride 2%
It is amide local anesthetic used for lubrication and pain prevention as topical anesthetic regimen
Sponsors & Collaborators
-
Jinnah Postgraduate Medical Centre
lead OTHER_GOV
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-11-22
- Primary Completion
- 2025-12-06
- Completion
- 2025-12-06
More Related Trials
-
Effect of Inflated Versus Non-inflated Endotracheal Tube on Sore Throat
NCT06218836 ·Status: COMPLETED ·Phase: NA
-
Effect of Lidocaine 1% and 2% in the Tube Cuff on Postoperative Sore Throat and Cough
NCT03792776 ·Status: UNKNOWN ·Phase: NA
-
Effect of Saline Lubrication on Post-intubation Complications
NCT02492646 ·Status: COMPLETED ·Phase: NA
-
Sore Throat After Intubation Using Glidescope With Stylet and Bougie
NCT04371094 ·Status: COMPLETED ·Phase: NA
-
Postoperative Sore Throat: Interest of the Videolaryngoscope
NCT05614414 ·Status: COMPLETED ·Phase: NA
-
Postoperative Sore Throat in Children: Comparison Between Two Supraglottic Devices, Ambu® AuraOnce™ Laryngeal Mask Airway (LMA) and I-Gel®.
NCT03140228 ·Status: COMPLETED ·Phase: NA
-
Incidence of Sore Throat With Traditional Intubation Blades or Glidescope Blade
NCT02033564 ·Status: COMPLETED ·Phase: NA
-
Bolus vs. Continuous IV Lidocaine Against Post-Extubation Cough in Post-Thyroidectomy Patients
NCT06040034 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of Topical Lidocaine Spraying on the Vocal Cords Before Intubation During Robotic Surgery: a Randomized Controlled Trial
NCT07154628 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
The Effects of Bimanual Laryngoscopy on Post-Operative Sore Throat in Adults
NCT01459354 ·Status: UNKNOWN
-
Comparison of Lidocaine and Remifentanil for the Effect on Responses to the Endotracheal Tube During Emergence From General Anesthesia
NCT01082458 ·Status: COMPLETED ·Phase: NA
-
A Prospective,Randomised, Open Label Study for Comparison of the Incidence and Severity of Postoperative Sore Throat (POST) Using C-MAC Video Laryngoscope and Traditional Macintosh Laryngoscope for Intubation
NCT05531617 ·Status: COMPLETED ·Phase: NA
-
Effects of Three Airway Instruments on the Incidence of Postoperative Sore Throat
NCT06515808 ·Status: COMPLETED
-
POST: Comparison of Macintosh Laryngoscope vs Video Laryngoscope in Patients Intubated by Anaesthesia Trainee
NCT04334616 ·Status: COMPLETED ·Phase: NA
-
Innovative Endotracheal Tube Design Reduces Postoperative Laryngeal Injury
NCT06108271 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Trial Comparing the Laryngeal Tube Suction Disposable and the Supreme Laryngeal Mask Airway
NCT02856672 ·Status: COMPLETED ·Phase: NA
-
Comparing the Efficacy Between Lignocaine Given Via MADgic Atomizer and Lignocaine Pump Spray
NCT06213116 ·Status: COMPLETED ·Phase: NA
-
Gender Specific Differences in Postoperative Sore Throat for Ambu® AuraGain™ Laryngeal Mask
NCT04915534 ·Status: COMPLETED ·Phase: NA
-
Air Versus Lignocaine for Endotracheal Tube Cuff Inflation and Effect on Postoperative Sore Throat and Intracuff Pressure
NCT07315490 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2/PHASE3
-
The Effect of Local Anesthetic Techniques on Hemodynamic Response and Postoperative Sore Throat in Double-Lumen Tubes
NCT06705595 ·Status: COMPLETED ·Phase: NA
-
Intubating Conditions During Propofol-remifentanil Anesthesia With Topical Lidocaine
NCT01489683 ·Status: COMPLETED ·Phase: NA
-
Insertion of Laryngeal Mask Airways and Postoperative Sore Throat
NCT06713343 ·Status: COMPLETED ·Phase: NA
-
Ultrasound-guided Thyroid Cartilage Plane Block for Awake Intubation
NCT06065475 ·Status: COMPLETED ·Phase: NA
-
The Effects of GMA-TULIP, I-gel, and BlockBuster Laryngeal Mask in Laparoscopic Surgeries With Trendelenburg Position Under General Anesthesia
NCT06766253 ·Status: RECRUITING ·Phase: NA
-
No Post Intubation Laryngeal Symptoms
NCT05383417 ·Status: COMPLETED ·Phase: NA