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Does Passive Movement Increase Glucose Uptake Into Muscle?

NCT06704126 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 11

Last updated 2025-08-11

No results posted yet for this study

Summary

This study aims to examine the blood sugar response after a meal, and how three different movement protocols may impact the blood sugar level.

Participants will visit the lab on three different occasions. Before each visit the participant will eat a meal we give them and have a cannula (a needle with a tube) put in their arm to allow blood sampling for the visit.

Visit A will be the participant just having their legs moved by the machine, visit B will be the participant having their legs moved by the machine with the addition of blood pressure cuffs on their thighs, and visit C will just be the participant sitting still on the machine.

Conditions

  • Glucose
  • Insulin
  • Blood Flow Restriction Therapy
  • Blood Flow Velocity

Interventions

OTHER

Passive movement

This study will use a passive movement protocol delivered on a Biodex isokinetic dynamometer at 1Hz for 60 seconds on, 60 seconds off, for a total of 30 minutes.

OTHER

Passive movement with blood flow restriction

This study will use a passive movement protocol delivered on a Biodex isokinetic dynamometer at 1Hz for 60 seconds on, 60 seconds off, for a total of 30 minutes. During the 60 seconds on of passive movement training, blood flow restriction cuffs which will be applied to the legs, will be inflated to cause 80% arterial blood flow occlusion.

Sponsors & Collaborators

  • Lancaster University

    lead OTHER

Principal Investigators

  • Paul Hendrickse, PhD · Lancaster University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-12-01
Primary Completion
2025-07-11
Completion
2025-07-11

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06704126 on ClinicalTrials.gov