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Caloric Restriction, Exercise, and Glucoregulation in Humans

NCT00777621 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 69

Last updated 2016-02-12

No results posted yet for this study

Summary

Weight loss induced by caloric restriction alone (CR) and by exercise alone (EX) result in similar effects on blood glucose and insulin. The purpose of this study is to assess the hypothesis that weight loss through caloric restriction plus exercise will result in greater improvements on glucose tolerance and insulin action than similar weight losses through CR or EX alone.

Conditions

Interventions

OTHER

Calorie Restriction

This group will undergo a 20% reduction in energy intake without any change in energy expenditure.

OTHER

Exercise

This group will undergo a 20% increase in energy expenditure by exercising without any change in energy intake.

OTHER

Calorie Restriction and Exercise

This group will undergo 10% reduction in energy intake and a 10% increase in energy expenditure via exercise.

Sponsors & Collaborators

  • National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

    collaborator NIH

  • St. Louis University

    lead OTHER

Principal Investigators

  • Edward P Weiss, PhD · St. Louis University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
45 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-04-30
Primary Completion
2015-03-31
Completion
2015-03-31

Countries

  • United States

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00777621 on ClinicalTrials.gov