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Effect of Chronic Feeding of Inulin And Methylcellulose on Colonic Fermentation

NCT06551961 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 35

Last updated 2024-11-15

No results posted yet for this study

Summary

To determine the effect on tolerance and gas production from chronic feeding of fermentable fibre (inulin) incorporated into a gel forming fibre (methylcellulose) compared with placebo (maltodextrin)

Conditions

  • Irritable Bowel Syndrome

Interventions

DIETARY_SUPPLEMENT

methylcellulose

2.5 and 5 gm Methylcelllose heated to create a gel

DIETARY_SUPPLEMENT

inulin

2.5 and 5 gm inulin powder dissolved in water

DIETARY_SUPPLEMENT

maltodextrin

2.5 and 5gm maltodextrin dissolved in water

Sponsors & Collaborators

  • University of Nottingham

    lead OTHER

  • University of East Anglia

    collaborator OTHER

Principal Investigators

  • Robin C Spiller, MD · University of Nottingham

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-09-30
Primary Completion
2025-06-30
Completion
2025-06-30

Countries

  • United Kingdom

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06551961 on ClinicalTrials.gov