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Modulation of Intestinal Barrier Function and Inflammation Via Butyrate-promoting Dietary Fibre

NCT05058131 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2022-04-21

No results posted yet for this study

Summary

This study examines how a fermentable dietary fibre known to promote butyrate production impacts intestinal barrier function, intestinal microbiota, intestinal inflammation, and gastrointestinal symptoms in patients with microscopic colitis.

Conditions

  • Microscopic Colitis

Interventions

DIETARY_SUPPLEMENT

Dietary fibre

Dietary fibre as a powder, 24 g per day for 6 weeks

DIETARY_SUPPLEMENT

Placebo compound

Maltodextrin powder, 24 g per day for 6 weeks

Sponsors & Collaborators

  • Örebro University, Sweden

    lead OTHER

Principal Investigators

  • Robert J Brummer, MD, PhD · Örebro University, Sweden

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-11-03
Primary Completion
2022-12-30
Completion
2022-12-30

Countries

  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05058131 on ClinicalTrials.gov