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Dietary Nitrate and Physiological Aging

NCT02593305 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 23

Last updated 2019-10-14

Study results available
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Summary

The main purpose/s of this study is to examine the effects of 4 weeks of dietary nitrate supplementation on peripheral chemoreceptor sensitivity, spontaneous baroreflex sensitivity, and blood pressure responsiveness to a variety of physiological stressors in older healthy adults. We will also examine the effect of dietary nitrate supplementation on measures of central artery stiffness and aortic blood pressure in older adults. Lastly, we will also recruit a group of young subjects in order to help characterize the age-related changes associated with the physiological outcome measures of the present study.

Conditions

  • Aging

Interventions

DIETARY_SUPPLEMENT

Super Beets

Nitrate rich beetroot powder (10g/day) for 4 weeks

DIETARY_SUPPLEMENT

Super Beets Placebo

Nitrate deficient beetroot powder (10g/day) for 4 weeks

Sponsors & Collaborators

  • Neogenis Laboratories

    collaborator OTHER

  • Darren P Casey

    lead OTHER

Principal Investigators

  • Darren Casey, PhD. · University of Iowa

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-10-31
Primary Completion
2017-04-28
Completion
2017-04-28

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02593305 on ClinicalTrials.gov