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Ischemic Postconditioning in Carotid Surgery

NCT06359756 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2026-03-27

No results posted yet for this study

Summary

Analyzing changes in cerebral oximetry, transcranial Doppler and biomarkers of neuronal ischemic injury and blood-brain barrier integrity assessing the safety and efficacy of ischemic postconditioning in carotid surgery (IPCT).

Conditions

  • Ischemic Postconditioning
  • Carotid Surgery
  • Stroke
  • Carotid Artery Diseases

Interventions

PROCEDURE

Ischemic postconditioning in carotid surgery

After the initial declamping of the carotid artery the procedure is performed with 6 cycles of reperfusion of 30 seconds each (clamping of the internal carotid artery) which are successively followed by 6 cycles of ischemia lasting 30 seconds (clamping of the internal carotid artery). Clamping is done on the unaltered ICA, at the clamping site prior to performing CEA above the plaque termination point.

PROCEDURE

Eversion Carotid Endarterectomy

Standard Eversion Carotid Endarterectomy

Sponsors & Collaborators

  • Institute for Cardiovascular Diseases Dedinje

    lead OTHER

Principal Investigators

  • Nenad Ilijevski, PhD · Institute for Cardiovascular Diseases Dedinje

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
50 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-09-01
Primary Completion
2026-01-01
Completion
2026-01-01

Countries

  • Serbia

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06359756 on ClinicalTrials.gov