Remote Ischemic Conditioning and Platelet Dysfunction
NCT03125681 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 58
Last updated 2019-04-04
Summary
The purpose of this study is to evaluate the effects of remote ischemic conditioning on platelet function during off-pump coronary artery bypass surgery.
Conditions
- Platelet Function
Interventions
- PROCEDURE
-
Remote ischemic conditioning
In the RIC group, RIC is performed before and after coronary anastomoses by 5 minutes limb ischemia and reperfusion with pneumatic cuff up to 200 mmHg repeated by four times.
- PROCEDURE
-
Control
In the control group, all the procedures will be same with RIC group, except for the fact that the three-way stopcock between the pneumatic cuff and the cuff inflator was opened and therefore the cuff pressure did not increase.
Sponsors & Collaborators
-
Seoul National University Hospital
lead OTHER
Principal Investigators
-
Yunseok Jeon, M.D., Ph. D. · Seoul National University Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 20 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-05-11
- Primary Completion
- 2019-01-31
- Completion
- 2019-02-09
Countries
- South Korea
Study Locations
More Related Trials
-
Effect of Remote Ischemic Preconditioning in Patient Undergoing Cardiac Bypass Surgery
NCT00397163 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Remote Ischaemic Preconditioning in Patients With Atherosclerosis Undergoing Vascular Surgery
NCT02689414 ·Status: COMPLETED ·Phase: NA
-
Effect of Beta-blocker on Cardioprotective Effect of Remote Ischemic Conditioning
NCT03169426 ·Status: COMPLETED ·Phase: PHASE4
-
Clinical Value of Remote Ischemic Preconditioning
NCT01740102 ·Status: COMPLETED ·Phase: NA
-
Effects of Remote Ischemic PreConditioning in Off-pump Versus On-pump Coronary Artery Bypass Grafting(RIPCON)
NCT01608984 ·Status: UNKNOWN ·Phase: PHASE1
-
Preoperative Dual Antiplatelet Therapy: Platelet Function and Influence of Cardiopulmonary Bypass
NCT02979158 ·Status: COMPLETED ·Phase: NA
-
Study on the Myocardial Protective Effect of Upper Limb Ischemic Preconditioning in Patients Undergoing Off-pump Coronary Artery Bypass Grafting
NCT03340181 ·Status: UNKNOWN ·Phase: NA
-
Application of Remote Ischemic Preconditioning in Patients Undergoing Open Heart Surgeries
NCT01906918 ·Status: UNKNOWN ·Phase: NA
-
Cell Salvage and Retrograde Autologous Priming
NCT04792814 ·Status: COMPLETED
-
Impact of Remote Ischemic Preconditioning Preceding Coronary Artery Bypass Grafting on Inducing nEuroprotection
NCT02177981 ·Status: COMPLETED ·Phase: NA
-
Re-infusion of Unwashed Shed Blood During Off-pump Surgery
NCT06358079 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
SAfety and EFficacy of Bridging Antithrombotic Therapy During Elective Non-cardiac Surgery
NCT04675801 ·Status: UNKNOWN
-
Remote Ischemic Preconditioning in Coronary Artery Bypass Grafting With Cold Crystalloid Cardioplegic Arrest
NCT01406678 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Long-term Remote Ischemic Preconditioning Improves Myocardial Perfusion and Prognosis of Patients After CABG
NCT04779008 ·Status: RECRUITING ·Phase: NA
-
Study Of Factors Favoring The Onset Of Novo Atrial Fibrillation In The Immediate Aftermath Of Coronary Artery Bypass Surgery
NCT02042547 ·Status: COMPLETED
-
The Effect of 6% Hydroxyethyl Starch 130/0.4 on Blood Loss and Coagulation in Patients Medicated With Antiplatelet Agents Prior to Off-Pump Coronary Bypass Graft Surgery
NCT01051206 ·Status: COMPLETED ·Phase: PHASE4
-
Loop Isolation-based Uploading Pre-conditioning
NCT03766529 ·Status: UNKNOWN
-
Effect of Non-anemic Iron Deficiency on Outcome Following Off-pump Coronary Revascularization
NCT06399627 ·Status: RECRUITING
-
Evaluation of Platelet Aggregability in the Release of CABG in Patients With ACS With DAPT.
NCT02516267 ·Status: COMPLETED ·Phase: NA
-
Ischaemia-réperfusion During the Coronary Surgery With Beating Heart
NCT01771978 ·Status: UNKNOWN ·Phase: PHASE3
-
Effect of Remote Ischaemic Preconditioning on Clinical Outcomes in CABG Surgery
NCT01247545 ·Status: COMPLETED ·Phase: PHASE3
-
The Efficacy and Safety of Ramosetron in Patients Undergoing Off Pump Coronary Artery Bypass Surgery
NCT02139241 ·Status: COMPLETED ·Phase: NA
-
Intraoperative Hemodynamics in CABG
NCT05125315 ·Status: UNKNOWN
-
Exploration of Cerebral Pathophysiology During and After CABG Using CPB
NCT02941380 ·Status: COMPLETED
-
Effect of Remote Ischemic Preconditioning on the Incidence of Acute Kidney Injury in Patients Undergoing Coronary Artery Bypass Graft Surgery
NCT02981680 ·Status: COMPLETED ·Phase: NA