Application of Remote Ischemic Preconditioning in Patients Undergoing Open Heart Surgeries
NCT01906918 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 120
Last updated 2013-11-28
Summary
Strategies for myocardial protection during open heart surgeries are desired. Several experimental studies have shown beneficial effects of remote ischemic preconditioning (RIPC). The underlying mechanisms are not totally understood. This study intends to evaluate molecular mechanisms involved with RIPC on myocardium of patients underwent open heart surgeries.
Conditions
- Coronary Artery Disease
- Valvular Heart Disease
Interventions
- PROCEDURE
-
IRPC, Remote preconditioning
The patients will be submitted to 5 minutes of upper limb compression by cuff followed by 5 minutes of reperfusion. This cycle will be repeated 4 times.
Sponsors & Collaborators
-
University of Campinas, Brazil
lead OTHER
Principal Investigators
-
Orlando Petrucci, MD, PhD · University of Campinas
-
Fany Lima, RN · University of Campinas
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-08-31
- Primary Completion
- 2015-08-31
- Completion
- 2015-08-31
Countries
- Brazil
Study Locations
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