The Effects of Pain and Pain Relief on Peripheral Nerve Excitability
NCT06356376 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 30
Last updated 2024-04-10
Summary
This study will assess changes in nerve excitability of C-fibers, and changes in sympathetic or parasympathetic tone, when the subject experiences pain and pain relief.
The investigators will continuously measure blood pressure, heart rate, respiration rate, gastric motility, sympathetic skin response and C-fiber excitability while using thermal stimuli before and after an analgesic.
Conditions
- Analgesia
Interventions
- DEVICE
-
Heat Stimulation
Heat stimulation at a painful, but to the subject tolerable level.
Sponsors & Collaborators
-
Lundbeck Foundation
collaborator OTHER -
University of Aarhus
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2023-12-20
- Primary Completion
- 2024-04-30
- Completion
- 2024-04-30
Countries
- Denmark
Study Locations
More Related Trials
-
Mechanisms of Neuropathic Pain: Investigation by Contact Heat Evoked Potential
NCT00173420 ·Status: UNKNOWN
-
The Analgesic Effect of Auditory Inputs and Its Relation to Psychological and Neurobiological Mechanisms
NCT03410563 ·Status: COMPLETED
-
Skin Conductance Fluctuations Per Sec and NRS to Monitor Pain
NCT01865344 ·Status: COMPLETED
-
Cold Pressor Test is Used in This Study to Assess the Effect of PF-06305591 on Pain Intensity Evoked by Cold in Healthy Male Subjects
NCT01812265 ·Status: COMPLETED ·Phase: PHASE1
-
Profile of Pain and Unpleasant Sensations in Patients With Referred Pain
NCT03926364 ·Status: COMPLETED
-
Effects of Acute Pain on Cognitive Performance in Young Adults
NCT05625776 ·Status: COMPLETED ·Phase: NA
-
Pain Perception and the Autonomic Nervous System
NCT06667895 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Brain Activation During Thermal Stimulation in Neuropathic Pain
NCT00525018 ·Status: UNKNOWN
-
Internet-based Cognitive Behavioral Therapy and Physiotherapy in Persons With Chronic Widespread Pain
NCT04624139 ·Status: COMPLETED ·Phase: NA
-
Conditioned Pain Modulation in Localized vs Widespread Chronic Low Back Pain
NCT05972395 ·Status: UNKNOWN
-
Pain Processing In Relation To Breathing
NCT06169917 ·Status: RECRUITING ·Phase: NA
-
Experimental Pain in Parkinsons
NCT05981261 ·Status: RECRUITING ·Phase: NA
-
Can the Perception of a Treatment Influence Pain Processing - an Examination of Psychological and Neurobiological Mechanisms
NCT03109860 ·Status: COMPLETED
-
Therapeutic Strategies During Exposure to Pain in an Experimental Design
NCT03146832 ·Status: COMPLETED ·Phase: NA
-
Influence of Expectations on Change in Pain Perception After a 3 Min Wallsquat Exercise.
NCT03678662 ·Status: COMPLETED ·Phase: NA
-
Experiences of Pain in Healthy Adults
NCT06611267 ·Status: COMPLETED ·Phase: NA
-
Audio-enhanced Analgesia in Healthy Subjects
NCT01835275 ·Status: COMPLETED ·Phase: NA
-
Pain Neuroscience Education in Old Adults.
NCT03523949 ·Status: WITHDRAWN ·Phase: NA
-
Central Sensitisation and Postoperative Pain
NCT04220697 ·Status: UNKNOWN ·Phase: NA
-
Descriptive Study of Pain, Anxiety and Depression
NCT00378274 ·Status: COMPLETED
-
Nutrition Care in Patients Living With Chronic Pain
NCT06277232 ·Status: RECRUITING ·Phase: NA
-
Psychophysical Correlates of Pain Reduction by Topical Analgesic Compounds
NCT02322164 ·Status: COMPLETED
-
Detection of Electrodermal Activity in Pain 1
NCT06678217 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Muscle Synergies in Pain and Pain Anticipation
NCT07251387 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Clinical and Scientific Assessment of Pain and Painful Disorders
NCT02707029 ·Status: RECRUITING