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Conditioned Pain Modulation in Localized vs Widespread Chronic Low Back Pain

NCT05972395 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 75

Last updated 2023-08-02

No results posted yet for this study

Summary

This study aims to compare function of the body's endogenous pain modulation system between people with localized low back pain versus widespread body pain. Endogenous pain modulation refers to the body's natural ability to inhibit one pain stimulus by applying a second pain stimulus. This study will assess pain inhibition by measuring pressure pain thresholds at the low back before and during cold water hand immersion. The researchers hypothesize that those with widespread body pain will have worse functioning of pain inhibition compared to those with localized low back pain only. The results may provide insights into personalized chronic pain management approaches.

Conditions

  • Chronic Low-back Pain

Interventions

OTHER

Localized vs Widespread Mechanical Pain Hypersensitivity

Based on pressure pain threshold mapping, participants will be classified as having either localized mechanical pain hyperalgesia (hyperalgesia limited to the lumbosacral region) or widespread mechanical pain hyperalgesia (hyperalgesia extending beyond the lumbosacral region).

Sponsors & Collaborators

  • Ahram Canadian University

    lead OTHER

Principal Investigators

  • Amal Fawzy, Ph.d · Faculty of Physical Therapy, Ahram Canadian University

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-07-28
Primary Completion
2024-02-25
Completion
2024-03-01

Countries

  • Egypt

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05972395 on ClinicalTrials.gov