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Oral Dexamethasone for Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy

NCT06288035 · Status: RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 814

Last updated 2024-03-12

No results posted yet for this study

Summary

Postoperative nausea and vomiting (PONV) are common complications after laparoscopic cholecystectomy. This study aims to evaluate the efficacy of the administration of prophylactic oral dexamethasone at night before surgery in preventing PONV after elective laparoscopic cholecystectomy.

Conditions

  • Postoperative Nausea and Vomiting

Interventions

DRUG

Dexamethasone Oral

Patients in the intervention group will receive oral 8 mg dexamethasone at night before surgery. The time of dexamethasone administration will be recorded.

DRUG

Dexamethasone

Patients in the control group will receive intravenous 8 mg dexamethasone just before or at the induction of anesthesia. The dexamethasone ampule will be diluted in a 10 ml syringe and given in at least one minute to avoid unpleasant sensations in injection.

Sponsors & Collaborators

  • Mansoura University

    lead OTHER

Principal Investigators

  • Moataz M Emara, MD, EDAIC · Mansoura University Hospital

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-03-04
Primary Completion
2025-03-31
Completion
2025-03-31

Countries

  • Egypt

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06288035 on ClinicalTrials.gov