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An Evaluation the Effect of Superhydration Versus Dextrose 10% for Prevention of Post Operative Nausea and Vomiting After Laparoscopic Cholecystectomy (prospective Randomised Controlled Study)

NCT06847594 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 204

Last updated 2025-02-26

No results posted yet for this study

Summary

The goal of this clinical trial is to learn if Dextrose 10% or superhydration works to prevent postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy.

. The main questions it aims to answer are:

Does Dextrose 10% or superhydration lower the number of times participants gets an episode of nausea and vomititng after laparoscopic cholecystectomy surgery? Researchers will compare Dextrose 10% versus superhydration to a placebo (a look-alike substance that contains no drug) to see if glucose 10% or superhydation can work to prevent postoperative nausea and vomiting.

Participants will:

Take Dextrose 10% or superhydration or a placebo in the operation monitored for 4 hours after surgery to check on their nausea and vomiting state

Conditions

  • Postoperative Nausea and Vomiting (PONV)

Interventions

DRUG

ringer lactate (20ml/kg)

ringer lactate 20 ml/kg over the first 90 to 120 minutes after induction intraoperatively

DRUG

Dextrose 10%

Dextrose 10% 250 ml over 60 minutes

Sponsors & Collaborators

  • Ain Shams University

    lead OTHER

Principal Investigators

  • Aya H. M. Ahmad, Assistant professor, MD · Ain Shams University Faculty of Medicine

  • Wael A. M. Abdelwahab, Assistant professor, MD · Ain Shams University Faculty of Medicine

  • Mohamed A. Elgendy, Assistant professor, MD · Ain Shams University Faculty of Medicine

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
21 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-02-25
Primary Completion
2024-09-25
Completion
2024-10-10

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06847594 on ClinicalTrials.gov