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Effects of Intraoperative Dexamethasone and Ondansetron on Postoperative Nausea and Vomiting in Microvascular Decompression Surgery

NCT03685032 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 54

Last updated 2018-09-26

No results posted yet for this study

Summary

Postoperative nausea and vomiting (PONV) is a common problem and may lead to catastrophic complications, especially in neurosurgical cases. The aim of this study was to evaluate the effects of dexamethasone and ondansetron for preventing PONV in patients who underwent microvascular decompression surgery (MVD).

Conditions

  • Microvascular Decompression Surgery
  • Postoperative Nausea and Vomiting

Interventions

DRUG

Dexamethasone

The 4 mg of dexamethasone in 1 ml intravenous was administrated after patient received general anesthesia

DRUG

Ondansetron

The 4 mg of ondansetron in 2 ml intravenous was administrated at the end of the operation.

DRUG

0.9% Sodium Chloride Injection

The 0.9% sodium chloride in 1 ml intravenous was administrated after patient received general anesthesia. At the end of operation, the 0.9% sodium chloride in 2 ml intravenous was administrated.

Sponsors & Collaborators

  • Khon Kaen University

    lead OTHER

Principal Investigators

  • Pornthep Kasemsiri, MD · Khon Kaen University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-08-07
Primary Completion
2016-02-16
Completion
2016-02-16

Countries

  • Thailand

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03685032 on ClinicalTrials.gov