MedTrace Logo

Prophylaxis Against Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy

NCT06017167 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 70

Last updated 2023-08-30

No results posted yet for this study

Summary

The aim of the study is to compare antiemetic effects between dexmedetomidine and ondansteron in the first group versus dexamethasone and ondansteron in the second group.

The primary outcome in this study is incidence of postoperative nausea and vomiting after laparoscopic cholecystectomy.

The secondary outcomes are:

* The severity of post operative nausea and vomiting.
* Use of rescue antiemetic drugs.
* Postoperative pain and sedation.

Conditions

  • Postoperative Nausea and Vomiting
  • Laparoscopic Cholecystectomy

Interventions

DRUG

Ondansetron 4mg + dexmedetomidine 0.5 ug/kg + normal saline .

compare antiemetic effects between dexmedetomidine and ondansetron in the first group versus dexamethasone and ondansetron in the second group

DRUG

Ondansetron 4mg + dexamethasone 8mg + normal saline.

Group II: Ondansetron 4mg + dexamethasone 8mg + normal saline.

Sponsors & Collaborators

  • Tanta University

    lead OTHER

Principal Investigators

  • Mohamed A. Lotfy, PHD · Assistant Professor of Anesthesia and Intensive Care, Tanta Univ

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-09-15
Primary Completion
2023-09-30
Completion
2023-10-31

Countries

  • Egypt

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06017167 on ClinicalTrials.gov