The Effect Of Resuscitation Guided By Two Different Dynamic Parameters On Time To Normalization Of The Capillary Refill Time In Adult Patients With Septic Shock
NCT06122909 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 90
Last updated 2025-04-29
Summary
The aim of this study is to compare the effect of resuscitation guided by Left ventricular outflow tract-velocity time integral (LVOT-VTI) variation versus the effect of resuscitation guided by inferior vena cava (IVC) variation on time to normalization of the capillary refill time in adult patients with septic shock, amount of resuscitation fluids, rate of vasopressor and ICU length of stay.
Conditions
- Septic Shock
- Resuscitation
Interventions
- DRUG
-
Group VTI
Group VTI will receive resuscitation guided by LVOT-VTI variation after PLR test.
- DRUG
-
Group IVC
Group IVC will receive resuscitation guided by IVC diameter variation after PLR test.
Sponsors & Collaborators
-
Mansoura University
collaborator OTHER -
Kasr El Aini Hospital
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 19 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-07-21
- Primary Completion
- 2025-01-01
- Completion
- 2025-01-01
Countries
- Egypt
Study Locations
More Related Trials
-
Comparison And Outcomes Of Fluid Resucitation With 0.9% Normal Saline And 5% Albumin In Cirrhosis Patients With Sepsis Induced Hypotension
NCT02462902 ·Status: COMPLETED ·Phase: NA
-
Peripheral Perfusion Versus Lactate Targeted Fluid Resuscitation in Septic Shock
NCT03762005 ·Status: UNKNOWN ·Phase: NA
-
Effect of Fluid Deresuscitation With Central Venous Pressure Target 0-4 mmHg in Septic Shock Patients
NCT04156451 ·Status: COMPLETED ·Phase: NA
-
Effects of Induced Moderate Hypothermia on ARDS Patients Under Venovenous ExtraCorporeal Membrane Oxygenation
NCT05306392 ·Status: UNKNOWN ·Phase: NA
-
Variation in Fluids Administered in Shock
NCT03190408 ·Status: COMPLETED
-
The Validity of Peripheral Perfusion Index to Predict Fluid Responsiveness
NCT03805321 ·Status: COMPLETED
-
Physiological Effects of 38°C vs. 22°C Fluid Therapy in Critically Ill Patients
NCT04576806 ·Status: WITHDRAWN ·Phase: NA
-
Small Volume Fluid Challenge as a Predictor of Fluid Responsiveness in Patients With Circulatory Failure
NCT03622099 ·Status: COMPLETED
-
The Impact of the Fluid Resuscitation on the Venous Volume and Flow Characteristics in Hypovolemic Shock
NCT02474056 ·Status: WITHDRAWN
-
Sodium Bicarbonate Ringer's Solution Versus Normal Saline for Early Fluid Resuscitation in Patients With Sepsis
NCT04621981 ·Status: UNKNOWN ·Phase: NA
-
Optimizing Fluid Resuscitation in Adults With Major Burns: A Randomized Trial of Burn Navigator™ Versus Parkland Formula
NCT07307599 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Extension of the RUSH Protocol for Volume Responsiveness
NCT03285269 ·Status: WITHDRAWN
-
Vexus-guided Fluid Management in Patients With Septic Shock After the Resuscitation Phase
NCT06227702 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Resuscitation Fluid Choice and Clinical Outcomes
NCT02641119 ·Status: COMPLETED
-
A Prospective Observational Study of the Expectations and Physiological Effects of Fluid Bolus Therapy
NCT03178578 ·Status: UNKNOWN
-
Fluid Resuscitation In Trauma: What Are The Best Strategies And Fluids?
NCT05738265 ·Status: UNKNOWN
-
Fluid Management Surgical Patients in Intensive Care Unit.
NCT03455296 ·Status: COMPLETED ·Phase: NA
-
Hemodynamic Optimization By Non-Invasive Determination Of Cardiac Output In Critically Ill Patients
NCT01309724 ·Status: COMPLETED ·Phase: NA
-
Strong Albumin Solutions in Patients With Septic Shock
NCT05208242 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Mini Bolus for Fluid Challenge Responsiveness in the Emergency Department
NCT05369559 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Low-chlorine Vs High-chlorine Crystalloids in Septic Shock Adults
NCT04365010 ·Status: UNKNOWN ·Phase: PHASE4
-
Emergency Department (ED) Flow-directed Fluid Optimization Resuscitation Trial (EFFORT)
NCT01128413 ·Status: TERMINATED ·Phase: NA
-
Fluid Balance in the ICU - Interventions to Minimize Fluids in Patients With Septic Shock
NCT02473718 ·Status: COMPLETED ·Phase: NA
-
Restricted or Liberal Fluid for Haemodynamic Resuscitation in Sepsis
NCT05453565 ·Status: NOT_YET_RECRUITING
-
Bicarbonated Ringer's Solution Versus Lactated Ringer's Solution in Patients With Septic Shock
NCT04449757 ·Status: UNKNOWN ·Phase: NA