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Mini Bolus for Fluid Challenge Responsiveness in the Emergency Department

NCT05369559 · Status: RECRUITING · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 1000

Last updated 2024-07-09

No results posted yet for this study

Summary

Intravascular volume expansion is a common intervention in critically ill patients with acute circulatory failure.we test the hypothesis that a mini-bolus fluid challenge, of either 50 ml , can predict fluid responsiveness in spontaneously breathing patients with hemodynamic instability.

Conditions

  • Fluid Therapy

Interventions

COMBINATION_PRODUCT

Mini bolus 50

receiving a "mini-bolus A":50 ml of crystalloid solution, regularly infused over 30 seconds

DIAGNOSTIC_TEST

passive leg rising test

Passive leg raising technique: Initially, the patient is placed semi-recumbent with the head of the bed at 45°. After recording baseline measurement, the head of the bed is lowered and the legs are elevated to 45° for 2 minutes

Sponsors & Collaborators

  • University of Monastir

    lead OTHER

Principal Investigators

  • Semir Nouira, Prof · University Hospital Fattouma Bourguiba Monastir , Emergency Department .

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-03-03
Primary Completion
2024-08-22
Completion
2025-05-22

Countries

  • Tunisia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05369559 on ClinicalTrials.gov