The Use of Submucosal Dexamethasone After Periodontal Surgery

Summary

The aim of this study is to evaluate the effectiveness of submucosal 8 mg (2 mL) dexamethasone on postoperative pain, swelling, chewing efficiency, trismus, healing, and discomfort after periodontal flap surgery

Conditions

• Periodontal Pocket
• Pain
• Swelling/ Edema
• Patient Satisfaction
• Periodontitis

Interventions

DRUG

submucosal 8 mg (2 mL) dexamethasone application

The mucoperiosteal flap was applied. After operation, submucosal dexamethasone 8 mg (2 mL) was applied to the operation area as a test group.

DRUG

submucosal 2 mL 0.9% isotonic sodium chloride application

The mucoperiosteal flap was applied. After operation, 2 mL 0.9% isotonic sodium chloride was applied to the operation area as a control group

Sponsors & Collaborators

• Yuzuncu Yıl University

  lead OTHER

Principal Investigators

• Dicle Altindal, DDS · Yuzuncu Yıl University

• Anas ALSAFADI, PhD · Special dental clinic

• Basem ALSHUJAA, PhD · Special dental clinic

• Ahmet Cemil Talmac, PhD · Yuzuncu Yıl University

• Bilal Ege, PhD · Adiyaman University

• Metin Calisir, PhD · Adiyaman University

• Nazli Zeynep Alpaslan, PhD · Yuzuncu Yıl University

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Model

CROSSOVER

Eligibility

Min Age

19 Years

Max Age

40 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2021-08-12

Primary Completion

2022-04-29

Completion

2022-04-29

Countries

• Turkey (Türkiye)

Study Locations