Use of Ozone Gel as an Antimicrobial in Treatment of Periodontitis
NCT05905445 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 21
Last updated 2023-06-15
Summary
Periodontitis is an inflammatory disease that destroys tooth-supporting structures through oral bacterial plaque. ozone gel's act as an antimicrobial effect as an adjunct to conventional periodontal therapy (scaling and root planning). exposure of bacteria to ozone leads to the oxidation of the phospholipids and lipoproteins that comprise the bacterial cell membrane. Ozone gel has the potential to play an anti-inflammatory role in the treatment of periodontitis by monitoring both clinical and biological parameters.
Conditions
- Periodontal Pocket
- Periodontitis
Interventions
- DRUG
-
ozone gel
the activity of omega-3 in the ozone gel may be advantageous as a host-modulating agent in the supplemental treatment of periodontitis
Sponsors & Collaborators
-
Ghufran Falih Hassan
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-03-09
- Primary Completion
- 2022-09-09
- Completion
- 2022-09-09
Countries
- Iraq
Study Locations
More Related Trials
-
Micro-Needling Technique Using Ozonated Olive Oil in Periodontal Diseases
NCT06990282 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Ozone Gel Application in Controlled Type 2 Diabetic Patients With Periodontitis
NCT05538078 ·Status: UNKNOWN ·Phase: NA
-
Effect of Ozone Oil After Non-surgical Periodontal Treatment
NCT05838209 ·Status: UNKNOWN ·Phase: NA
-
Treatment of Periodontitis by Conventional 4 Weekly Sections or Within 24 Hours
NCT02215460 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy of Subgingivally Delivered Doxycycline Plus Ketoprofen Gel as an Adjunct to Non-surgical Periodontal Treatment
NCT02538224 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Effect of Ozone Use in Intracanal Irrigation on Oxidative Stress Level in Teeth With Asymptomatic Apical Periodontitis
NCT07171762 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Impact of Nonsurgical Periodontal Therapy on Oral Health Related Quality of Life
NCT06143085 ·Status: RECRUITING ·Phase: NA
-
Advanced Oxidation Protein Product and Monocyte Chemoattractant Protein-1 in Periodontal Disease
NCT02848378 ·Status: COMPLETED
-
Evaluation of the Systemic Burden of Non-surgical Periodontal Therapy: A Randomized Clinical Trial on Five Different Treatment Protocols
NCT07077122 ·Status: RECRUITING ·Phase: NA
-
Alternative Antibiotic Regimen in Periodontitis Treatment
NCT04353362 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Antibiotics on Systemic Inflammation
NCT05115201 ·Status: COMPLETED ·Phase: NA
-
Hydroxylated Polymethoxy Flavones Solid Dispersion in Treatment of Periodontitis
NCT05546788 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
Analysis of the Impact of Contemporary Subgingival Debridement Techniques on Immunological Biomarkers in Gingival Crevicular Fluid
NCT07243145 ·Status: COMPLETED
-
Impact of Guided Biofilm Therapy on Epithelial and Mesenchymal Biomarkers in Periodontitis Patients
NCT07286916 ·Status: RECRUITING ·Phase: NA
-
Zinc Stents for the Treatment of Gingivitis
NCT06888440 ·Status: COMPLETED ·Phase: NA
-
The Effect of Adjunctive Therapies in Regenerative Treatment of Stage III Grade C Periodontitis
NCT05447026 ·Status: COMPLETED ·Phase: NA
-
Efficacy of Photodynamic Therapy and LASER Disinfection in Periodontal Therapy for Treatment of Periodontitis
NCT06305533 ·Status: RECRUITING ·Phase: NA
-
Local Injection of Periodontal Pocket Method for the Treatment of Gingivitis
NCT05812300 ·Status: COMPLETED ·Phase: NA
-
Periostin and Non-Surgical Periodontal Treatment
NCT04332965 ·Status: COMPLETED ·Phase: NA
-
Effect of Nonsurgical Periodontal Therapy Verses Oral Hygiene Instructions on Patients With Chronic Periodontitis
NCT02208739 ·Status: COMPLETED ·Phase: NA
-
Treatment Of Shallow Periodontal Pockets Using PRF As an Adjunct To Scaling And Root Planing In Periodontitis Patients
NCT05890157 ·Status: UNKNOWN ·Phase: NA
-
Intervention Study of Two Protocols for Non-surgical Treatment of Chronic Periodontitis
NCT02168621 ·Status: UNKNOWN ·Phase: NA
-
The Role of Probiotics and Dietary Interventions in the Treatment of Periodontitis
NCT06944938 ·Status: COMPLETED ·Phase: NA
-
IL-1β and S1P Levels After Periodontal Therapy: A Split-Mouth Study
NCT06930430 ·Status: COMPLETED ·Phase: NA
-
Periocline as an Adjunct to Scaling and Root Planing for Adult Periodontitis
NCT00529555 ·Status: COMPLETED ·Phase: PHASE3