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StrokeCog-BBB to Study Cognitive Outcomes Following Stroke

NCT06116630 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 350

Last updated 2024-04-18

No results posted yet for this study

Summary

The goal of this observational study is to learn about cognitive outcomes in stroke patients. The main question it aims to answer are: 1. Is blood-brain barrier permeability compromised for years after stroke, 2. Is a blood biomarker of imbalanced angiogenesis dysregulated in chronic stroke and 3. Are there biomarkers that separately or together predicts cognitive decline after stroke, and are other MRI, blood, and clinical characteristics that are associated. Participants will undergo cognitive testing and MRIs two years apart. Researchers will compare cognitive outcomes in non-stroke patients who have cardiovascular risk factors to understand the effects of stroke on these outcomes.

Conditions

Interventions

DIAGNOSTIC_TEST

DCE-MRI

Both groups will undergo DCE-MRIs.

Sponsors & Collaborators

Principal Investigators

  • Marion Buckwalter, MD · Stanford University

Eligibility

Min Age
45 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-05-17
Primary Completion
2027-12-31
Completion
2027-12-31

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06116630 on ClinicalTrials.gov