A Study in Adults With Advanced Classical Hodgkin's Lymphoma (cHL) in Brazil Treated With Brentuximab Vedotin Together With Chemotherapy Compared to Chemotherapy Alone
NCT06104878 · Status: WITHDRAWN · Type: OBSERVATIONAL
Last updated 2024-03-06
Summary
The main aim of this study conducted in Brazil is to understand if there is a difference in the length of time that Classical Hodgkin's Lymphoma (cHL) does not grow or spread further (also called progression free survival or PFS), and in the length of time that participants live with cHL if they are treated with Brentuximab Vedotin in combination with chemotherapy (A+AVD) or chemotherapy alone (ABVD).
A+AVD includes Brentuximab Vedotin + Doxorubicin + Vinblastine + Dacarbazine; ABVD includes Doxorubicin + Bleomycin + Vinblastine + Dacarbazine.
The study will be conducted by reviewing and collecting already existing medical records.
Conditions
Interventions
- OTHER
-
No Intervention
No Intervention will be administered in this study.
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Study Director · Takeda
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-12-31
- Primary Completion
- 2024-10-31
- Completion
- 2024-10-31
- FDA Drug
- Yes
Countries
- Brazil
Study Locations
More Related Trials
-
A Study of Nivolumab Plus Brentuximab Vedotin Versus Brentuximab Vedotin Alone in Patients With Advanced Stage Classical Hodgkin Lymphoma, Who Are Relapsed/ Refractory or Who Are Not Eligible for Autologous Stem Cell Transplant,
NCT03138499 ·Status: TERMINATED ·Phase: PHASE3
-
Clinical Trial of Brentuximab Vedotin in Classical Hodgkin Lymphoma
NCT03646123 ·Status: TERMINATED ·Phase: PHASE2
-
Patient-reported and Clinical Outcomes in Adults With Relapsed or Refractory Hodgkin's Lymphoma Receiving Brentuximab Vedotin
NCT03440788 ·Status: UNKNOWN
-
A Study of Brentuximab Vedotin With Doxorubicin, Vinblastine and Dacarbazine in Adults With Hodgkin Lymphoma in India
NCT06831370 ·Status: RECRUITING ·Phase: PHASE4
-
Induction Chemo w/ABVD Followed by Brentuximab Vedotin Consolidation in Newly Diagnosed, Non-Bulky Stage I/II Hodgkin Lymphoma
NCT01578967 ·Status: COMPLETED ·Phase: NA
-
Brentuximab Vedotin Associated With Chemotherapy in Untreated Patients With Hodgkin Lymphoma.
NCT02292979 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase 1 Study of Brentuximab Vedotin Given Sequentially and Combined With Multi-Agent Chemotherapy for CD30-Positive Mature T-Cell and NK-Cell Neoplasms
NCT01309789 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy in Treating Patients With Previously Untreated Advanced Hodgkin's Lymphoma
NCT00041210 ·Status: UNKNOWN ·Phase: PHASE3
-
Brentuximab Vedotin Plus AVD in Limited-stage Hodgkin Lymphoma
NCT01534078 ·Status: COMPLETED ·Phase: PHASE2
-
Brentuximab Vedotin and Combination Chemotherapy in Treating Older Patients With Previously Untreated Stage II-IV Hodgkin Lymphoma
NCT01476410 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Hodgkin's Lymphoma
NCT00005584 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Combination Chemotherapy With or Without Rituximab in Treating Participants With Stage III-IV Classic Hodgkin Lymphoma
NCT00654732 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Pembrolizumab (MK-3475) vs. Brentuximab Vedotin in Participants With Relapsed or Refractory Classical Hodgkin Lymphoma (MK-3475-204/KEYNOTE-204)
NCT02684292 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy in Treating Patients With Advanced Hodgkin's Disease
NCT00003421 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab
NCT05675410 ·Status: RECRUITING ·Phase: PHASE3
-
Brentuximab Vedotin and Nivolumab for the Treatment of Relapsed/Refractory Classic Hodgkin Lymphoma Previously Treated With Brentuximab Vedotin or Checkpoint Inhibitors
NCT05039073 ·Status: RECRUITING ·Phase: PHASE2
-
Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma
NCT03907488 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
BREntuximab Vedotin in SEcond LIne Therapy BEfore Transplant
NCT04378647 ·Status: RECRUITING ·Phase: PHASE2
-
RT or No RT Following Chemotherapy in Treating Patients With Stage III/IV Hodgkin's Disease
NCT00002462 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Study Evaluating the Safety and Efficacy of Venetoclax (GDC-0199) Plus Bendamustine + Rituximab (BR) in Comparison With BR or Venetoclax Plus Rituximab in Participants With Relapsed and Refractory Follicular Non-Hodgkin's Lymphoma (fNHL)
NCT02187861 ·Status: COMPLETED ·Phase: PHASE2
-
Brentuximab Vedotin and Nivolumab for the Treatment of Patients With Relapsed/Refractory Classical Hodgkin Lymphoma
NCT04561206 ·Status: RECRUITING ·Phase: PHASE2
-
Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Hodgkin's Lymphoma
NCT00003389 ·Status: COMPLETED ·Phase: PHASE3
-
A Trial Comparing Chemotherapy Versus Novel Immune Checkpoint Inhibitor (Pembrolizumab) Plus Chemotherapy in Treating Relapsed/Refractory Classical Hodgkin Lymphoma
NCT05711628 ·Status: WITHDRAWN ·Phase: PHASE3
-
Study of Brentuximab Vedotin in Patients With R/R PTCL Treated With Gemcitabine
NCT03496779 ·Status: COMPLETED ·Phase: PHASE2
-
Brentuximab Vedotin Combined With AVD Chemotherapy in Patients With Newly Diagnosed Early Stage, Unfavorable Risk Hodgkin Lymphoma
NCT01868451 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA